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research published recently in Neuron, Marcos Frank, PhD, Assistant Professor of Neuroscience, at the University of Pennsylvania School of Medicine, postdoctoral researcher Sara Aton, PhD, and colleagues describe for the first time how cellular changes in the sleeping brain promote the formation of memories.
"This is the the animal goes to sleep it's like you’ve thrown a switch, and all of a sudden, everything is turned on that's necessary for making synaptic changes that form the basis of memory formation. It's very striking."
The team used an experimental model of cortical plasticity first real direct insight into how the brain, on a cellular level, changes the strength of its connections during sleep," Frank says.The findings, says Frank, reveal that the brain during sleep is fundamentally different from the brain during wakefulness. "We find that the biochemical changes are simply not happening in the neurons of animals that are awake," Frank says. "And when